![PFE-360 Size:Contact sales@xcessbio.com for quotation Chemical Name: (2E)-2-(4-fluorobenzenesulfonyl)-3-[1-(3-nitrobenzenesulfonyl)-1H-pyrrol-2-yl]prop-2-enenitrile](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M21838_1635223365.gif?v=1635223366)
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Chemical Name: (2E)-2-(4-fluorobenzenesulfonyl)-3-[1-(3-nitrobenzenesulfonyl)-1H-pyrrol-2-yl]prop-2-enenitrile
rapidly induces HemSC apoptosis
NAE activates Nedd8 (Neural precursor cell expressed
10) stably expressed in 1321N1 human astrocytoma cells
PFE-360 Size:Contact [email protected] for quotation Chemical Name: (2E)-2-(4-fluorobenzenesulfonyl)-3-[1-(3-nitrobenzenesulfonyl)-1H-pyrrol-2-yl]prop-2-enenitrilePFE 360 (PF 06685360) is a potent, selective, brain penetrated and orally active leucine rich repeat kinase 2 (LRRK2) inhibitor with a mean IC50 of 2. 3 nM in vivo. Product information CAS Number: 1527475 61 1 Molecular Weight: 308. 34 Formula: C16H16N6O Chemical Name: 1 methyl 4 [4 (morpholin 4 yl) 7H pyrrolo[2,3 d]pyrimidin 5 yl] 1H pyrrole 2 carbonitrile Smiles: CN1C=C(C=C1C#N)C1=CNC2=NC=NC(=C12)N1CCOCC1 InChiKey: IYQTYHISVSPMSU UHFFFAOYSA N InChi:
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